No. Dungeon Defenders II was originally going to have a MOBA mode, but after receiving feedback from our community, we decided to kill the MOBA. It's dead. Its corpse was burned to ashes. The ashes were placed into a vessel, pushed to sea and set alight by a flaming arrow shot from the shore. It was beautiful. Lots of flames.
Dungeon Defenders II is an Action Tower Defense game just like the original Dungeon Defenders.